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Structure paper

TitleGluD1 binds GABA and controls inhibitory plasticity.
Journal, issue, pagesScience, Vol. 382, Page 1389-1394, Year 2023
Publish dateNov 9, 2022 (structure data deposition date)
AuthorsPiot, L. / Heroven, C. / Bossi, S. / Zamith, J. / Malinauskas, T. / Johnson, C. / Wennagel, D. / Stroebel, D. / Charrier, C. / Aricescu, A.R. ...Piot, L. / Heroven, C. / Bossi, S. / Zamith, J. / Malinauskas, T. / Johnson, C. / Wennagel, D. / Stroebel, D. / Charrier, C. / Aricescu, A.R. / Mony, L. / Paoletti, P.
External linksScience / PubMed:38060673
MethodsX-ray diffraction
Resolution1.63 - 2.18 Å
Structure data

PDB-8blj:
Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1), apo state
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

PDB-8bn2:
Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with D-Serine
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

PDB-8bn5:
Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with GABA
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-DSN:
D-SERINE

ChemComp-ABU:
GAMMA-AMINO-BUTANOIC ACID

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / ion channel / ligand binding domain / glutamate receptor / apo state / D-Serine / GABA

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