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Structure paper

TitleToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 120, Page e2304378120-e2304378120, Year 2023
Publish dateSep 20, 2022 (structure data deposition date)
AuthorsCanals, A. / Pieretti, S. / Muriel-Masanes, M. / El Yaman, N. / Plecha, S.C. / Thomson, J.J. / Fabrega-Ferrer, M. / Perez-Luque, R. / Krukonis, E.S. / Coll, M.
External linksProc. Natl. Acad. Sci. USA / PubMed:37428913
MethodsX-ray diffraction
Resolution1.75 - 3.25 Å
Structure data

PDB-8b4b:
ToxR bacterial transcriptional regulator bound to 19 bp ompU promoter DNA
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-8b4c:
ToxR bacterial transcriptional regulator bound to 20 bp toxT promoter DNA
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

PDB-8b4d:
ToxR bacterial transcriptional regulator bound to 40 bp toxT promoter DNA
Method: X-RAY DIFFRACTION / Resolution: 2.64 Å

PDB-8b4e:
ToxR bacterial transcriptional regulator bound to 25 bp toxT promoter DNA
Method: X-RAY DIFFRACTION / Resolution: 3.25 Å

Chemicals

ChemComp-CD:
Unknown entry

ChemComp-NH4:
AMMONIUM ION

ChemComp-HOH:
WATER

Source
  • vibrio cholerae (bacteria)
KeywordsDNA BINDING PROTEIN / bacterial transcription / activation complex

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