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Structure paper

TitleStructure-Guided Approach for the Development of MUC1-Glycopeptide-Based Cancer Vaccines with Predictable Responses.
Journal, issue, pagesJacs Au, Vol. 4, Page 150-163, Year 2024
Publish dateAug 31, 2022 (structure data deposition date)
AuthorsBermejo, I.A. / Guerreiro, A. / Eguskiza, A. / Martinez-Saez, N. / Lazaris, F.S. / Asin, A. / Somovilla, V.J. / Companon, I. / Raju, T.K. / Tadic, S. ...Bermejo, I.A. / Guerreiro, A. / Eguskiza, A. / Martinez-Saez, N. / Lazaris, F.S. / Asin, A. / Somovilla, V.J. / Companon, I. / Raju, T.K. / Tadic, S. / Garrido, P. / Garcia-Sanmartin, J. / Mangini, V. / Grosso, A.S. / Marcelo, F. / Avenoza, A. / Busto, J.H. / Garcia-Martin, F. / Hurtado-Guerrero, R. / Peregrina, J.M. / Bernardes, G.J.L. / Martinez, A. / Fiammengo, R. / Corzana, F.
External linksJacs Au / PubMed:38274250
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-8axh:
Crystal structure of a MUC1-like glycopeptide containing the unnatural L-4-hydroxynorvaline in complex with scFv-SM3
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-A2G:
2-acetamido-2-deoxy-alpha-D-galactopyranose

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM

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