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-Structure paper
Title | Design of rigid protein-protein interaction inhibitors enables targeting of undruggable Mcl-1. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 120, Page e2221967120-e2221967120, Year 2023 |
Publish date | Aug 26, 2022 (structure data deposition date) |
![]() | Hargreaves, D. / Carbajo, R.J. / Bodnarchuk, M.S. / Embrey, K. / Rawlins, P.B. / Packer, M. / Degorce, S.L. / Hird, A.W. / Johannes, J.W. / Chiarparin, E. / Schade, M. |
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Methods | X-ray diffraction |
Resolution | 1.99 Å |
Structure data | ![]() PDB-8av9: |
Chemicals | ![]() ChemComp-VF8: ![]() ChemComp-HOH: |
Source |
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![]() | APOPTOSIS / MCL1 / FAB / MACROCYCLE / MCL1-FAB_55_C6HIS / IMMUNE SYSTEM |