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Structure paper

TitleAn anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa.
Journal, issue, pagesNat. Chem. Biol., Vol. 19, Page 1158-1166, Year 2023
Publish dateJul 5, 2022 (structure data deposition date)
AuthorsHarding, C.J. / Bischoff, M. / Bergkessel, M. / Czekster, C.M.
External linksNat. Chem. Biol. / PubMed:37386135
MethodsX-ray diffraction
Resolution1.4 - 2.84 Å
Structure data

PDB-8ac7:
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-8ac9:
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T
Method: X-RAY DIFFRACTION / Resolution: 2.351 Å

PDB-8acg:
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP_T E340A mutant
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

PDB-8ack:
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
Method: X-RAY DIFFRACTION / Resolution: 1.784 Å

PDB-8acr:
Structure of Pseudomonas aeruginosa aminopeptidase, PaAP
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-CAC:
CACODYLATE ION

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsHYDROLASE / WT / Full-length / Truncation / E340A mutant / Truncation bound to ERWGHDFIK

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