+Search query
-Structure paper
Title | Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. |
---|---|
Journal, issue, pages | J Enzyme Inhib Med Chem, Vol. 37, Page 1773-1811, Year 2022 |
Publish date | May 13, 2022 (structure data deposition date) |
![]() | Rohrig, U.F. / Majjigapu, S.R. / Vogel, P. / Reynaud, A. / Pojer, F. / Dilek, N. / Reichenbach, P. / Ascencao, K. / Irving, M. / Coukos, G. ...Rohrig, U.F. / Majjigapu, S.R. / Vogel, P. / Reynaud, A. / Pojer, F. / Dilek, N. / Reichenbach, P. / Ascencao, K. / Irving, M. / Coukos, G. / Michielin, O. / Zoete, V. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.551 Å |
Structure data | ![]() PDB-7zv3: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-RCT: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
|
![]() | OXIDOREDUCTASE / Dioxygenase / Heme-containing enzyme / Structure-based drug design / Triazole / Small-molecule inhibitor |