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TitleDeveloping a Copper(II) Agent Based on His-146 and His-242 Residues of Human Serum Albumin Nanoparticles: Integration To Overcome Cisplatin Resistance and Inhibit the Metastasis of Nonsmall Cell Lung Cancer.
Journal, issue, pagesJ. Med. Chem., Vol. 65, Page 9447-9458, Year 2022
Publish dateJun 9, 2022 (structure data deposition date)
AuthorsJiang, M. / Zhang, Z. / Li, W. / Man, X. / Sun, H. / Liang, H. / Yang, F.
External linksJ. Med. Chem. / PubMed:35786921
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-7y2d:
HSA-Cu agent complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-PLM:
PALMITIC ACID

ChemComp-IC4:
13-methoxy-~{N},~{N}-dimethyl-2-oxa-4-thia-6,7$l^{4}-diaza-3$l^{3}-cupratricyclo[7.4.0.0^{3,7}]trideca-1(9),5,7,10,12-pentaen-5-amine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMETAL BINDING PROTEIN / Complex

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