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-Structure paper
Title | From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases. |
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Journal, issue, pages | J. Med. Chem., Vol. 67, Page 754-773, Year 2024 |
Publish date | Apr 26, 2022 (structure data deposition date) |
![]() | Zhang, L. / Li, Y. / Tian, C. / Yang, R. / Wang, Y. / Xu, H. / Zhu, Q. / Chen, S. / Li, L. / Yang, S. |
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Methods | X-ray diffraction |
Resolution | 2.376 Å |
Structure data | ![]() PDB-7xmk: |
Chemicals | ![]() ChemComp-IOD: ![]() ChemComp-GO4: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / RIPK1 / kinase / complex / inhibitor |