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TitleA variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein.
Journal, issue, pagesCell Res., Vol. 32, Page 1068-1085, Year 2022
Publish dateFeb 15, 2022 (structure data deposition date)
AuthorsPang, W. / Lu, Y. / Zhao, Y.B. / Shen, F. / Fan, C.F. / Wang, Q. / He, W.Q. / He, X.Y. / Li, Z.K. / Chen, T.T. ...Pang, W. / Lu, Y. / Zhao, Y.B. / Shen, F. / Fan, C.F. / Wang, Q. / He, W.Q. / He, X.Y. / Li, Z.K. / Chen, T.T. / Yang, C.X. / Li, Y.Z. / Xiao, S.X. / Zhao, Z.J. / Huang, X.S. / Luo, R.H. / Yang, L.M. / Zhang, M. / Dong, X.Q. / Li, M.H. / Feng, X.L. / Zhou, Q.C. / Qu, W. / Jiang, S. / Ouyang, S. / Zheng, Y.T.
External linksCell Res. / PubMed:36357786
MethodsX-ray diffraction
Resolution2.41 Å
Structure data

PDB-7wxz:
Crystal structure of the recombinant protein HR121 from the S2 protein of SARS-CoV-2
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
KeywordsVIRAL PROTEIN / SARS-CoV-2 / S2 / recombinant protein / HR121 / fusion intermediate

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