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-Structure paper
Title | Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1' Subsite Binder with Short Peptides. |
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Journal, issue, pages | J. Med. Chem., Vol. 65, Page 13253-13263, Year 2022 |
Publish date | Feb 15, 2022 (structure data deposition date) |
Authors | Tabuse, H. / Abe-Sato, K. / Kanazawa, H. / Yashiro, M. / Tamura, Y. / Kamitani, M. / Hitaka, K. / Gunji, E. / Mitani, A. / Kojima, N. / Oka, Y. |
External links | J. Med. Chem. / PubMed:36137271 |
Methods | X-ray diffraction |
Resolution | 1.5 Å |
Structure data | PDB-7wxx: |
Chemicals | ChemComp-CA: ChemComp-ZN: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / Matrilysin / Matrin / Matrix metalloproteinase-7 / Pump-1 protease / Uterine metalloproteinase |