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TitleTargeting CDCP1 gene transcription coactivated by BRD4 and CBP/p300 in castration-resistant prostate cancer.
Journal, issue, pagesOncogene, Vol. 41, Page 3251-3262, Year 2022
Publish dateFeb 14, 2022 (structure data deposition date)
AuthorsJi, D. / Shang, G. / Wei, E. / Jia, Y. / Wang, C. / Zhang, Q. / Zeng, L.
External linksOncogene / PubMed:35513563
MethodsX-ray diffraction
Resolution1.16 - 1.24 Å
Structure data

PDB-7wwz:
BRD4-BD1 complexed with NEO2734
Method: X-RAY DIFFRACTION / Resolution: 1.16 Å

PDB-7wx2:
CBP-BrD complexed with NEO2734
Method: X-RAY DIFFRACTION / Resolution: 1.24 Å

Chemicals

ChemComp-7OW:
1,3-dimethyl-5-[2-(oxan-4-yl)-3-[2-(trifluoromethyloxy)ethyl]benzimidazol-5-yl]pyridin-2-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / BRD4 / Bromodomain / NEO2734 / Complex / PROTEIN BINDING / CBP

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