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Structure paper

TitleStructure of Ternary Complex of cGAS with dsDNA and Bound 5 -ppcpG(2 ,5 )pA
Journal, issue, pagesTo Be Published
Publish dateMay 10, 2022 (structure data deposition date)
AuthorsWu, S. / Gabelli, S.B. / Sohn, J.S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.51 Å
Structure data

PDB-7v0r:
Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -ppcpG(2 ,5 )pA
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

Chemicals

ChemComp-OKX:
[(2~{R},3~{R},4~{R},5~{R})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-[[oxidanyl(phosphonooxy)phosphoryl]methyl]phosphinic acid

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsTRANSFERASE/DNA / Complex / ppcpGpA / Magnesium / IMMUNE SYSTEM / TRANSFERASE-DNA complex

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