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-Structure paper
Title | Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses. |
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Journal, issue, pages | Immunity, Vol. 55, Page 1680-1692.e8, Year 2022 |
Publish date | Apr 10, 2022 (structure data deposition date) |
![]() | McLeod, B. / Mabrouk, M.T. / Miura, K. / Ravichandran, R. / Kephart, S. / Hailemariam, S. / Pham, T.P. / Semesi, A. / Kucharska, I. / Kundu, P. ...McLeod, B. / Mabrouk, M.T. / Miura, K. / Ravichandran, R. / Kephart, S. / Hailemariam, S. / Pham, T.P. / Semesi, A. / Kucharska, I. / Kundu, P. / Huang, W.C. / Johnson, M. / Blackstone, A. / Pettie, D. / Murphy, M. / Kraft, J.C. / Leaf, E.M. / Jiao, Y. / van de Vegte-Bolmer, M. / van Gemert, G.J. / Ramjith, J. / King, C.R. / MacGill, R.S. / Wu, Y. / Lee, K.K. / Jore, M.M. / King, N.P. / Lovell, J.F. / Julien, J.P. |
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Methods | X-ray diffraction |
Resolution | 2.18 Å |
Structure data | ![]() PDB-7unb: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-HOH: |
Source |
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![]() | IMMUNE SYSTEM / Pfs48/45 / human transmission-blocking antibodies / Plasmodium falciparum / Malaria |