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-Structure paper
Title | Preclinical Characterization of Vadadustat (AKB-6548), an Oral Small Molecule Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor, for the Potential Treatment of Renal Anemia. |
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Journal, issue, pages | J. Pharmacol. Exp. Ther., Vol. 383, Page 11-24, Year 2022 |
Publish date | Apr 7, 2022 (structure data deposition date) |
![]() | Zuk, A. / Si, Z. / Loi, S. / Bommegowda, S. / Hoivik, D. / Danthi, S. / Molnar, G. / Csizmadia, V. / Rabinowitz, M. |
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Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | ![]() PDB-7ump: |
Chemicals | ![]() ChemComp-FE2: ![]() ChemComp-A1Z: ![]() ChemComp-EDO: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / METAL BINDING PROTEIN / EGLN1 / PHD2 |