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Title | Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD. |
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Journal, issue, pages | Iscience, Vol. 26, Page 105783-105783, Year 2023 |
Publish date | Apr 3, 2022 (structure data deposition date) |
Authors | Chen, Y. / Prevost, J. / Ullah, I. / Romero, H. / Lisi, V. / Tolbert, W.D. / Grover, J.R. / Ding, S. / Gong, S.Y. / Beaudoin-Bussieres, G. ...Chen, Y. / Prevost, J. / Ullah, I. / Romero, H. / Lisi, V. / Tolbert, W.D. / Grover, J.R. / Ding, S. / Gong, S.Y. / Beaudoin-Bussieres, G. / Gasser, R. / Benlarbi, M. / Vezina, D. / Anand, S.P. / Chatterjee, D. / Goyette, G. / Grunst, M.W. / Yang, Z. / Bo, Y. / Zhou, F. / Beland, K. / Bai, X. / Zeher, A.R. / Huang, R.K. / Nguyen, D.N. / Sherburn, R. / Wu, D. / Piszczek, G. / Pare, B. / Matthies, D. / Xia, D. / Richard, J. / Kumar, P. / Mothes, W. / Cote, M. / Uchil, P.D. / Lavallee, V.P. / Smith, M.A. / Pazgier, M. / Haddad, E. / Finzi, A. |
External links | Iscience / PubMed:36514310 |
Methods | X-ray diffraction |
Resolution | 2.49 - 2.65 Å |
Structure data | PDB-7ul0: PDB-7ul1: |
Chemicals | ChemComp-NAG: ChemComp-NA: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN/Immune System / Pediatric neutralizing mAb / RBD-ridge-targeting / bind to both closed and open SARS-CoV-2 spike / Class-2 RBD-binding antibody / VIRAL PROTEIN / VIRAL PROTEIN-Immune System complex / IGHV3-53 Ab / Class-1 RBD-binding antibody |