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-Structure paper
Title | Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease. |
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Journal, issue, pages | Biomolecules, Vol. 12, Year 2022 |
Publish date | Mar 18, 2022 (structure data deposition date) |
Authors | Alhashimi, R.T. / Ghatge, M.S. / Donkor, A.K. / Deshpande, T.M. / Anabaraonye, N. / Alramadhani, D. / Danso-Danquah, R. / Huang, B. / Zhang, Y. / Musayev, F.N. ...Alhashimi, R.T. / Ghatge, M.S. / Donkor, A.K. / Deshpande, T.M. / Anabaraonye, N. / Alramadhani, D. / Danso-Danquah, R. / Huang, B. / Zhang, Y. / Musayev, F.N. / Abdulmalik, O. / Safo, M.K. |
External links | Biomolecules / PubMed:35625623 |
Methods | X-ray diffraction |
Resolution | 1.8 Å |
Structure data | PDB-7ud7: PDB-7ud8: |
Chemicals | ChemComp-HEM: ChemComp-MWC: ChemComp-HOH: ChemComp-OXY: ChemComp-MW0: |
Source |
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Keywords | OXYGEN TRANSPORT / hemoglobin / sickle cell disease / antisickling / NO release / oxygen equilibrium |