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Structure paper

TitleTREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics
Journal, issue, pagesto be published
Publish dateMar 9, 2022 (structure data deposition date)
AuthorsHemphill, W.O. / Harvey, S.E. / Simpson, S.R. / Smalley, T.L. / Salsbury, F.R. / Perrino, F.W. / Hollis, T.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.22 Å
Structure data

PDB-7u8y:
TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics
Method: X-RAY DIFFRACTION / Resolution: 2.22 Å

Chemicals

ChemComp-AZN:
ALIZARIN RED

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE/INHIBITOR / Inhibitor / Exonuclease / Immunotherapy / Complex / DNA BINDING PROTEIN / HYDROLASE-INHIBITOR complex

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