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TitlePhosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease.
Journal, issue, pagesCell Rep, Vol. 41, Page 111537-111537, Year 2022
Publish dateFeb 2, 2022 (structure data deposition date)
AuthorsPayliss, B.J. / Tse, Y.W.E. / Reichheld, S.E. / Lemak, A. / Yun, H.Y. / Houliston, S. / Patel, A. / Arrowsmith, C.H. / Sharpe, S. / Wyatt, H.D.M.
External linksCell Rep / PubMed:36288699
MethodsNMR (solution)
Structure data

PDB-7tuj:
NMR solution structure of the phosphorylated MUS81-binding region from human SLX4
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / SAP domain / disorder-to-order transition

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