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-Structure paper
Title | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum. |
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Journal, issue, pages | Eur. J. Med. Chem., Vol. 243, Page 114751-114751, Year 2022 |
Publish date | Nov 23, 2021 (structure data deposition date) |
Authors | Chheda, P.R. / Nieto, N. / Kaur, S. / Beck, J.M. / Beck, J.R. / Honzatko, R. / Kerns, R.J. / Nelson, S.W. |
External links | Eur. J. Med. Chem. / PubMed:36191407 |
Methods | X-ray diffraction |
Resolution | 2.5 - 2.7 Å |
Structure data | PDB-7sxl: PDB-7sxq: |
Chemicals | ChemComp-GOL: ChemComp-NA: ChemComp-CL: ChemComp-PEG: ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | REPLICATION / Transferase / DNA polymerase / exonulease / apicoplast / Plasmodium falciparum |