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-Structure paper
Title | Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme. |
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Journal, issue, pages | Protein Sci., Vol. 31, Page 882-899, Year 2022 |
Publish date | Aug 24, 2021 (structure data deposition date) |
![]() | Kesari, P. / Deshmukh, A. / Pahelkar, N. / Suryawanshi, A.B. / Rathore, I. / Mishra, V. / Dupuis, J.H. / Xiao, H. / Gustchina, A. / Abendroth, J. ...Kesari, P. / Deshmukh, A. / Pahelkar, N. / Suryawanshi, A.B. / Rathore, I. / Mishra, V. / Dupuis, J.H. / Xiao, H. / Gustchina, A. / Abendroth, J. / Labaied, M. / Yada, R.Y. / Wlodawer, A. / Edwards, T.E. / Lorimer, D.D. / Bhaumik, P. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-7ry7: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-EDO: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / SSGCID / Plasmepsin X / Plasmodium falciparum / PM10 / PMX / Structural Genomics / Seattle Structural Genomics Center for Infectious Disease |