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-Structure paper
Title | Rapid discovery and crystallography study of highly potent and selective butylcholinesterase inhibitors based on oxime-containing libraries and conformational restriction strategies. |
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Journal, issue, pages | Bioorg. Chem., Vol. 134, Page 106465-106465, Year 2023 |
Publish date | Dec 12, 2021 (structure data deposition date) |
![]() | Jing, L. / Wei, W. / Meng, B. / Chantegreil, F. / Nachon, F. / Martinez, A. / Wu, G. / Zhao, H. / Song, Y. / Kang, D. ...Jing, L. / Wei, W. / Meng, B. / Chantegreil, F. / Nachon, F. / Martinez, A. / Wu, G. / Zhao, H. / Song, Y. / Kang, D. / Brazzolotto, X. / Zhan, P. / Liu, X. |
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Methods | X-ray diffraction |
Resolution | 2.04 - 2.47 Å |
Structure data | ![]() PDB-7qhd: ![]() PDB-7qhe: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-MES: ![]() ChemComp-GOL: ![]() ChemComp-C0I: ![]() ChemComp-SIA: ![]() ChemComp-SO4: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-C4I: |
Source |
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![]() | HYDROLASE / Butyrylcholinesterase / Inhibitor / Complex |