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-Structure paper
Title | High-resolution structures of the bound effectors avadomide (CC-122) and iberdomide (CC-220) highlight advantages and limitations of the MsCI4 soaking system. |
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Journal, issue, pages | Acta Crystallogr D Struct Biol, Vol. 78, Page 290-298, Year 2022 |
Publish date | Sep 22, 2021 (structure data deposition date) |
Authors | Heim, C. / Hartmann, M.D. |
External links | Acta Crystallogr D Struct Biol / PubMed:35234143 |
Methods | X-ray diffraction |
Resolution | 1.52 - 1.8 Å |
Structure data | PDB-7ps9: PDB-7pso: |
Chemicals | ChemComp-ZN: ChemComp-8W7: ChemComp-HOH: ChemComp-EF2: ChemComp-PO4: ChemComp-835: |
Source |
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Keywords | SIGNALING PROTEIN / PROTEIN DEGRADATION / Immunomodulatory imide drug / E3 LIGASE / UBIQUITIN LIGASE |