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-Structure paper
Title | Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling. |
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Journal, issue, pages | Nat Commun, Vol. 13, Page 5439-5439, Year 2022 |
Publish date | Sep 14, 2021 (structure data deposition date) |
![]() | Zeke, A. / Takacs, T. / Sok, P. / Nemeth, K. / Kirsch, K. / Egri, P. / Poti, A.L. / Bento, I. / Tusnady, G.E. / Remenyi, A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.48 - 1.9 Å |
Structure data | ![]() PDB-7ppl: ![]() PDB-7ppm: ![]() PDB-7ppn: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-EOH: ![]() ChemComp-HOH: |
Source |
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![]() | SIGNALING PROTEIN / IRS1 / Phosphatase / SHP2 / insulin signaling / Insulin receptor substrate 1 / phosphopeptide / CD28 / signaling |