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TitleLetter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein.
Journal, issue, pagesHepatol Commun, Vol. 6, Page 3277-3278, Year 2022
Publish dateJul 9, 2021 (structure data deposition date)
AuthorsStruwe, M.A. / Clement, B. / Scheidig, A.
External linksHepatol Commun / PubMed:35560545
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-7p41:
Crystal Structure of human mARC1 A165T Variant
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-EFK:
oxidanyl(oxidanylidene)molybdenum

ChemComp-MTE:
PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER

ChemComp-B3P:
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • enterobacteria phage t4 (virus)
KeywordsMETAL BINDING PROTEIN / molybdenum Cofactor / molybdenum enzyme / molybdopterin / pyranopterin / mARC

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