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-Structure paper
Title | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 9238-9258, Year 2021 |
Publish date | Feb 3, 2021 (structure data deposition date) |
Authors | Meijer, F.A. / Saris, A.O.W.M. / Doveston, R.G. / Oerlemans, G.J.M. / de Vries, R.M.J.M. / Somsen, B.A. / Unger, A. / Klebl, B. / Ottmann, C. / Cossar, P.J. / Brunsveld, L. |
External links | J. Med. Chem. / PubMed:34008974 |
Methods | X-ray diffraction |
Resolution | 1.47 - 1.95 Å |
Structure data | PDB-7nec: PDB-7np5: PDB-7np6: PDB-7npc: |
Chemicals | ChemComp-U95: ChemComp-HOH: ChemComp-UKB: ChemComp-UK8: ChemComp-ULT: ChemComp-GOL: |
Source |
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Keywords | NUCLEAR PROTEIN / Nuclear receptor / Retinoic acid receptor-related orphan receptor gamma t / inverse agonist / Allosteric / Inhibitor |