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-Structure paper
Title | Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein-Protein Interaction. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 11614-11636, Year 2021 |
Publish date | Mar 20, 2019 (structure data deposition date) |
Authors | Muszak, D. / Surmiak, E. / Plewka, J. / Magiera-Mularz, K. / Kocik-Krol, J. / Musielak, B. / Sala, D. / Kitel, R. / Stec, M. / Weglarczyk, K. ...Muszak, D. / Surmiak, E. / Plewka, J. / Magiera-Mularz, K. / Kocik-Krol, J. / Musielak, B. / Sala, D. / Kitel, R. / Stec, M. / Weglarczyk, K. / Siedlar, M. / Domling, A. / Skalniak, L. / Holak, T.A. |
External links | J. Med. Chem. / PubMed:34313116 |
Methods | X-ray diffraction |
Resolution | 2.2 - 2.3 Å |
Structure data | PDB-6r3k: PDB-7nld: |
Chemicals | ChemComp-EDO: ChemComp-JQT: ChemComp-HOH: ChemComp-UGZ: |
Source |
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Keywords | IMMUNE SYSTEM / PD-L1 / PD-1 / immune checkpoint / cancer / inhibitor |