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TitleEstrogen Receptor Alpha Ligand Binding Domain in Complex with Aliphatic SERD S-C10(15)
Journal, issue, pagesTo Be Published
Publish dateJun 18, 2021 (structure data deposition date)
AuthorsFanning, S.W. / Mader, S.C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-7n9o:
Estrogen Receptor Alpha Ligand Binding Domain in Complex with Aliphatic SERD S-C10(15)
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-5YR:
10-{[3,17beta-dihydroxyestra-1,3,5(10)-trien-7beta-yl]sulfanyl}-N-methyl-N-propyldecanamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Breast Cancer / Selective Estrogen Receptor Degrader / Aliphatic SERD / Antagonist / Alpha Helical Bundle

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