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TitleDrug Resistant HIV-1 Protease (L10F, V32I, L33F, K45I, A71V, V82I, I84V) in Complex with DRV
Journal, issue, pagesTo Be Published
Publish dateMar 31, 2021 (structure data deposition date)
AuthorsLockbaum, G.J. / Schiffer, C.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.93 Å
Structure data

PDB-7maq:
Drug Resistant HIV-1 Protease (L10F, V32I, L33F, K45I, A71V, V82I, I84V) in Complex with DRV
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-017:
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE / medication, antiretroviral*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1 group m subtype b
KeywordsHYDROLASE/HYDROLASE INHIBITOR / drug resistance / HYDROLASE-HYDROLASE INHIBITOR complex

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