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TitleA Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex.
Journal, issue, pagesAcs Chem. Biol., Vol. 16, Page 1721-1736, Year 2021
Publish dateMar 24, 2021 (structure data deposition date)
AuthorsWaybright, J.M. / Clinkscales, S.E. / Barnash, K.D. / Budziszewski, G.R. / Rectenwald, J.M. / Chiarella, A.M. / Norris-Drouin, J.L. / Cholensky, S.H. / Pearce, K.H. / Herring, L.E. ...Waybright, J.M. / Clinkscales, S.E. / Barnash, K.D. / Budziszewski, G.R. / Rectenwald, J.M. / Chiarella, A.M. / Norris-Drouin, J.L. / Cholensky, S.H. / Pearce, K.H. / Herring, L.E. / McGinty, R.K. / Hathaway, N.A. / James, L.I.
External linksAcs Chem. Biol. / PubMed:34415726
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-7m5u:
Crystal structure of human MPP8 chromodomain in complex with peptidomimetic ligand UNC5246
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGENE REGULATION / chromodomain / peptidomimetic / chromatin

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