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-Structure paper
Title | Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 10333-10349, Year 2021 |
Publish date | Mar 22, 2021 (structure data deposition date) |
![]() | Zhang, M. / Aguilar, A. / Xu, S. / Huang, L. / Chinnaswamy, K. / Sleger, T. / Wang, B. / Gross, S. / Nicolay, B.N. / Ronseaux, S. ...Zhang, M. / Aguilar, A. / Xu, S. / Huang, L. / Chinnaswamy, K. / Sleger, T. / Wang, B. / Gross, S. / Nicolay, B.N. / Ronseaux, S. / Harvey, K. / Wang, Y. / McEachern, D. / Kirchhoff, P.D. / Liu, Z. / Stuckey, J. / Tron, A.E. / Liu, T. / Wang, S. |
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Methods | X-ray diffraction |
Resolution | 2.74 Å |
Structure data | ![]() PDB-7m4t: |
Chemicals | ![]() ChemComp-YQV: ![]() ChemComp-7PR: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / Inhibitor |