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TitleConformational flexibility determines the Nf2/merlin tumor suppressor functions.
Journal, issue, pagesMatrix Biol Plus, Vol. 12, Page 100074-100074, Year 2021
Publish dateMar 1, 2021 (structure data deposition date)
AuthorsPrimi, M.C. / Rangarajan, E.S. / Patil, D.N. / Izard, T.
External linksMatrix Biol Plus / PubMed:34337379
MethodsX-ray diffraction
Resolution1.606 Å
Structure data

PDB-7lwh:
Human neurofibromin 2/merlin residues 1-339 in complex with LATS1
Method: X-RAY DIFFRACTION / Resolution: 1.606 Å

Chemicals

ChemComp-IMD:
IMIDAZOLE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / actin / cancer / cell junction / cell migration / cell signaling / inositol phospholipid / neurofibromatosis type 2 / plasma membrane

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