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Structure paper

TitleComprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.
Journal, issue, pagesJ. Mol. Biol., Vol. 433, Page 167115-167115, Year 2021
Publish dateSep 11, 2019 (structure data deposition date)
AuthorsTeyra, J. / McLaughlin, M. / Singer, A. / Kelil, A. / Ernst, A. / Sicheri, F. / Sidhu, S.S.
External linksJ. Mol. Biol. / PubMed:34171344
MethodsX-ray diffraction
Resolution1.65 - 1.8 Å
Structure data

PDB-6ubh:
Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-7lul:
Structure of the MM2 Erbin PDZ variant in complex with a high-affinity peptide
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsSIGNALING PROTEIN / Phage display / directed evolution / -2 position / specificity / phage library

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