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-Structure paper
Title | Optimization of Versatile Oxindoles as Selective PI3K delta Inhibitors. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 11, Page 2461-2469, Year 2020 |
Publish date | Jul 23, 2020 (structure data deposition date) |
Authors | Methot, J.L. / Achab, A. / Christopher, M. / Zhou, H. / McGowan, M.A. / Trotter, B.W. / Fradera, X. / Lesburg, C.A. / Goldenblatt, P. / Hill, A. ...Methot, J.L. / Achab, A. / Christopher, M. / Zhou, H. / McGowan, M.A. / Trotter, B.W. / Fradera, X. / Lesburg, C.A. / Goldenblatt, P. / Hill, A. / Chen, D. / Otte, K.M. / Augustin, M. / Shah, S. / Katz, J.D. |
External links | Acs Med. Chem. Lett. / PubMed:33335668 |
Methods | X-ray diffraction |
Resolution | 2.12 - 2.42 Å |
Structure data | PDB-7jis: PDB-7jiu: |
Chemicals | ChemComp-VBS: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / PI3KDELTA KINASE / TRANSFERASE / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX / PI3KALPHA KINASE |