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| Title | AvmM catalyses macrocyclization through dehydration/Michael-type addition in alchivemycin A biosynthesis. |
|---|---|
| Journal, issue, pages | Nat Commun, Vol. 13, Page 4499-4499, Year 2022 |
| Publish date | Jul 19, 2021 (structure data deposition date) |
Authors | Zhu, H.J. / Zhang, B. / Wei, W. / Liu, S.H. / Xiang, L. / Zhu, J. / Jiao, R.H. / Igarashi, Y. / Bashiri, G. / Liang, Y. ...Zhu, H.J. / Zhang, B. / Wei, W. / Liu, S.H. / Xiang, L. / Zhu, J. / Jiao, R.H. / Igarashi, Y. / Bashiri, G. / Liang, Y. / Tan, R.X. / Ge, H.M. |
External links | Nat Commun / PubMed:35922406 |
| Methods | X-ray diffraction |
| Resolution | 2.09 - 2.5 Å |
| Structure data | ![]() PDB-7fe0: ![]() PDB-7fe5: ![]() PDB-7fe6: |
| Chemicals | ![]() ChemComp-CL: ![]() ChemComp-CAC: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-ZHU: |
| Source |
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Keywords | BIOSYNTHETIC PROTEIN / Alchivemycin / Michael addition / Macrocyclization / BIOSYNTHETIC PROTEIN/INHIBITOR / AvmM / BIOSYNTHETIC PROTEIN-INHIBITOR COMPLEX |
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streptomyces sp. nbrc 109436 (bacteria)
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