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-Structure paper
Title | Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. |
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Journal, issue, pages | Sci Rep, Vol. 12, Page 15440-15440, Year 2022 |
Publish date | May 12, 2021 (structure data deposition date) |
Authors | Ruf, S. / Rajagopal, S. / Kadnur, S.V. / Hallur, M.S. / Rani, S. / Kristam, R. / Swaminathan, S. / Zope, B.R. / Gondrala, P.K. / Swamy, I. ...Ruf, S. / Rajagopal, S. / Kadnur, S.V. / Hallur, M.S. / Rani, S. / Kristam, R. / Swaminathan, S. / Zope, B.R. / Gondrala, P.K. / Swamy, I. / Putta, V.P.R.K. / Kandan, S. / Zech, G. / Schreuder, H. / Rudolph, C. / Elvert, R. / Czech, J. / Birudukota, S. / Siddiqui, M.A. / Anand, N.N. / Mane, V.S. / Dittakavi, S. / Suresh, J. / Gosu, R. / Ramesh, M. / Yura, T. / Dhakshinamoorthy, S. / Kannt, A. |
External links | Sci Rep / PubMed:36104373 |
Methods | X-ray diffraction |
Resolution | 2.61 - 2.731 Å |
Structure data | PDB-7et7: PDB-7eu5: |
Chemicals | ChemComp-SAH: ChemComp-JCU: ChemComp-HOH: ChemComp-JDL: |
Source |
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Keywords | TRANSFERASE / NNMT |