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TitleSynthesis of a Coumarin-Based PPAR gamma Fluorescence Probe for Competitive Binding Assay.
Journal, issue, pagesInt J Mol Sci, Vol. 22, Year 2021
Publish dateMar 23, 2021 (structure data deposition date)
AuthorsYoshikawa, C. / Ishida, H. / Ohashi, N. / Itoh, T.
External linksInt J Mol Sci / PubMed:33919837
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-7efq:
Crystal structure of hPPARgamma ligand binding domain complexed with rosiglitazone-based fluorescence probe
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-J3F:
(5S)-5-[[4-[2-[[7-(diethylamino)-2-oxidanylidene-chromen-4-yl]-methyl-amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PPARgamma / rosiglitazone / coumarin / fluorescence probe / TZD

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