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TitleStructural analyses of a human lysyl-tRNA synthetase mutant associated with autosomal recessive nonsyndromic hearing impairment.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 554, Page 83-88, Year 2021
Publish dateMar 6, 2021 (structure data deposition date)
AuthorsWu, S. / Hei, Z. / Zheng, L. / Zhou, J. / Liu, Z. / Wang, J. / Fang, P.
External linksBiochem. Biophys. Res. Commun. / PubMed:33784510
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-7ea9:
Crystal Structure of human lysyl-tRNA synthetase Y145H mutant
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-KAA:
5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / lysyl-tRNA synthetase / LysRS / disease related mutant

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