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TitleCrystal Structure of double mutant Y115E Y117E human Secretory Glutaminyl Cyclase in complex with LSB-09
Journal, issue, pagesTo Be Published
Publish dateOct 8, 2020 (structure data deposition date)
AuthorsDileep, K.V. / Ihara, K. / Sakai, N. / Shirozu, M. / Zhang, K.Y.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-7d8e:
Crystal Structure of double mutant Y115E Y117E human Secretory Glutaminyl Cyclase in complex with LSB-09
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-GYO:
~{N}-[(1~{S},2~{S})-2-(2-methoxyphenyl)cyclopropyl]-3~{H}-benzimidazole-5-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Glutaminyl-peptide cyclotransferase / sQC / Alzheimer's disease / Pyroglutamate

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