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Structure paper

TitleEngineering Disulphide-Free Autonomous Antibody VH Domains to modulate intracellular pathways
Journal, issue, pagesTo Be Published
Publish dateOct 2, 2020 (structure data deposition date)
AuthorsFrosi, Y. / Lin, Y.C. / Jiang, S. / Ramlan, S.R. / Hew, K. / Asial, I. / Engman, A.H. / Goh, M. / Thean, D. / Nordlund, P. ...Frosi, Y. / Lin, Y.C. / Jiang, S. / Ramlan, S.R. / Hew, K. / Asial, I. / Engman, A.H. / Goh, M. / Thean, D. / Nordlund, P. / Lane, D.P. / Brown, C.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.668 Å
Structure data

PDB-7d6y:
eIF4E in Complex with a Disulphide-Free Autonomous VH Domain
Method: X-RAY DIFFRACTION / Resolution: 1.668 Å

Chemicals

ChemComp-MGO:
[[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / VH domain / Cap-Dependent Translation

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