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-Structure paper
Title | Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development. |
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Journal, issue, pages | J. Med. Chem., Vol. 63, Page 15541-15563, Year 2020 |
Publish date | Jul 29, 2020 (structure data deposition date) |
![]() | Wang, H. / Ren, B. / Liu, Y. / Jiang, B. / Guo, Y. / Wei, M. / Luo, L. / Kuang, X. / Qiu, M. / Lv, L. ...Wang, H. / Ren, B. / Liu, Y. / Jiang, B. / Guo, Y. / Wei, M. / Luo, L. / Kuang, X. / Qiu, M. / Lv, L. / Xu, H. / Qi, R. / Yan, H. / Xu, D. / Wang, Z. / Huo, C.X. / Zhu, Y. / Zhao, Y. / Wu, Y. / Qin, Z. / Su, D. / Tang, T. / Wang, F. / Sun, X. / Feng, Y. / Peng, H. / Wang, X. / Gao, Y. / Gong, W. / Yu, F. / Liu, X. / Wang, L. / Zhou, C. |
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Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | ![]() PDB-7cmw: |
Chemicals | ![]() ChemComp-DS9: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | ANTITUMOR PROTEIN / PARP1 / pamiparib / BGB-290 / transferase |