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-Structure paper
Title | Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. |
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Journal, issue, pages | Nat Commun, Vol. 11, Page 4417-4417, Year 2020 |
Publish date | Mar 29, 2020 (structure data deposition date) |
![]() | Fu, L. / Ye, F. / Feng, Y. / Yu, F. / Wang, Q. / Wu, Y. / Zhao, C. / Sun, H. / Huang, B. / Niu, P. ...Fu, L. / Ye, F. / Feng, Y. / Yu, F. / Wang, Q. / Wu, Y. / Zhao, C. / Sun, H. / Huang, B. / Niu, P. / Song, H. / Shi, Y. / Li, X. / Tan, W. / Qi, J. / Gao, G.F. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.35 - 2 Å |
Structure data | ![]() PDB-7bro: ![]() PDB-7brp: ![]() PDB-7c6s: ![]() PDB-7c6u: ![]() PDB-7d1m: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-U5G: ![]() ChemComp-K36: ![]() ChemComp-DMS: |
Source |
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![]() | VIRAL PROTEIN / 2019-nCoV main protease / The main protease of 2019-nCoV complexed with Boceprevir / SARS-CoV-2 / main protease / inhibitor / GC376 |