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-Structure paper
| Title | GSK137, a potent small-molecule BCL6 inhibitor with in vivo activity, suppresses antibody responses in mice. |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 297, Page 100928-100928, Year 2021 |
| Publish date | Dec 21, 2020 (structure data deposition date) |
 Authors | Pearce, A.C. / Bamford, M.J. / Barber, R. / Bridges, A. / Convery, M.A. / Demetriou, C. / Evans, S. / Gobbetti, T. / Hirst, D.J. / Holmes, D.S. ...Pearce, A.C. / Bamford, M.J. / Barber, R. / Bridges, A. / Convery, M.A. / Demetriou, C. / Evans, S. / Gobbetti, T. / Hirst, D.J. / Holmes, D.S. / Hutchinson, J.P. / Jayne, S. / Lezina, L. / McCabe, M.T. / Messenger, C. / Morley, J. / Musso, M.C. / Scott-Stevens, P. / Manso, A.S. / Schofield, J. / Slocombe, T. / Somers, D. / Walker, A.L. / Wyce, A. / Zhang, X.P. / Wagner, S.D. |
 External links | J. Biol. Chem. / PubMed:34274316 |
| Methods | X-ray diffraction |
| Resolution | 2.044 Å |
| Structure data |  PDB-7bde: |
| Chemicals |  ChemComp-TEQ:  ChemComp-GOL:  ChemComp-DMS:  ChemComp-HOH: |
| Source |
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 Keywords | TRANSCRIPTION / BTB DOMAIN / B-CELL LYMPHOMA / TRANSCRIPTIONAL REPRESSION TRANSCRIPTION / INHIBITOR |
homo sapiens (human)