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TitleCrystal structure of human CRM1, covalently modified by 2-mercaptoethanol on Cys528, in complex with RanGTP.
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 77, Page 70-78, Year 2021
Publish dateDec 3, 2020 (structure data deposition date)
AuthorsShaikhqasem, A. / Schmitt, K. / Valerius, O. / Ficner, R.
External linksActa Crystallogr. ,Sect. F / PubMed:33682791
MethodsX-ray diffraction
Resolution2.58 Å
Structure data

PDB-7b51:
Crystal structure of human CRM1 covalently modified by 2-mercaptoethanol at Cys528
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsNUCLEAR PROTEIN / Exportin / Inhibition

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