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-Structure paper
Title | An engineered variant of MECR reductase reveals indispensability of long-chain acyl-ACPs for mitochondrial respiration. |
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Journal, issue, pages | Nat Commun, Vol. 14, Page 619-619, Year 2023 |
Publish date | Nov 12, 2020 (structure data deposition date) |
Authors | Tanvir Rahman, M. / Kristian Koski, M. / Panecka-Hofman, J. / Schmitz, W. / Kastaniotis, A.J. / Wade, R.C. / Wierenga, R.K. / Kalervo Hiltunen, J. / Autio, K.J. |
External links | Nat Commun / PubMed:36739436 |
Methods | X-ray diffraction |
Resolution | 1.85 - 2.02 Å |
Structure data | PDB-7ayb: PDB-7ayc: |
Chemicals | ChemComp-CL: ChemComp-PO4: ChemComp-GOL: ChemComp-ACY: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / Medium-chain alcohol dehydrogenase / Mitochondrial trans-2-enoyl-CoA reductase / Fatty acid synthesis |