EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures.
ジャーナル・号・ページ	Proc. Natl. Acad. Sci. USA, Vol. 118, Year 2021
掲載日	2020年11月9日 (構造データの登録日)
著者	Delfosse, V. / Huet, T. / Harrus, D. / Granell, M. / Bourguet, M. / Gardia-Parege, C. / Chiavarina, B. / Grimaldi, M. / Le Mevel, S. / Blanc, P. ...Delfosse, V. / Huet, T. / Harrus, D. / Granell, M. / Bourguet, M. / Gardia-Parege, C. / Chiavarina, B. / Grimaldi, M. / Le Mevel, S. / Blanc, P. / Huang, D. / Gruszczyk, J. / Demeneix, B. / Cianferani, S. / Fini, J.B. / Balaguer, P. / Bourguet, W.
リンク	Proc. Natl. Acad. Sci. USA / PubMed:33361153
手法	X線回折
解像度	1.9 - 2.7 Å
構造データ	PDB-7ax8: Crystal structure of the hPXR-LBD in apo form (P43212 SG) 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-7ax9: Crystal structure of the hPXR-LBD in complex with cis-chlordane 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-7axa: Crystal structure of the hPXR-LBD in complex with clotrimazole 手法: X-RAY DIFFRACTION / 解像度: 2.26 Å PDB-7axb: Crystal structure of the hPXR-LBD in complex with endosulfan 手法: X-RAY DIFFRACTION / 解像度: 2.55 Å PDB-7axc: Crystal structure of the hPXR-LBD in complex with ferutinine 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-7axd: Crystal structure of the hPXR-LBD in complex with fipronil 手法: X-RAY DIFFRACTION / 解像度: 2.65 Å PDB-7axe: Crystal structure of the hPXR-LBD in complex with oxadiazon 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7axf: Crystal structure of the hPXR-LBD in complex with pretilachlor 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-7axg: Crystal structure of the hPXR-LBD in complex with tributyltin 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-7axh: Crystal structure of the hPXR-LBD in complex with alpha-zearalanol 手法: X-RAY DIFFRACTION / 解像度: 2.55 Å PDB-7axi: Crystal structure of the hPXR-LBD in complex with estradiol and cis-chlordane 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-7axj: Crystal structure of the hPXR-LBD in complex with estradiol and clotrimazole 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-7axk: Crystal structure of the hPXR-LBD in complex with estradiol and endosulfan 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-7axl: Crystal structure of the hPXR-LBD in complex with estradiol and heptachlor endo-epoxide 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å
化合物	ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-HOH: WATER ChemComp-S6H: (+)cis-chlordane ChemComp-IPA: ISOPROPYL ALCOHOL ChemComp-GOL: GLYCEROL ChemComp-CL6: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE / 薬剤, 抗真菌剤YM ChemComp-MPD: (4S)-2-METHYL-2,4-PENTANEDIOL / 沈殿剤YM ChemComp-S68: endosulfan ChemComp-27H: ferutinine ChemComp-S6W: fipronil ChemComp-S6Z: oxadiazon ChemComp-S6T: pretilachlor ChemComp-TBY: tributylstannanyl ChemComp-27J: alpha-zearalanol ChemComp-EST: ESTRADIOL / ホルモンYM ChemComp-S6E: (-)cis-chlordane ChemComp-S65*: heptachlor endo-epoxide
由来	homo sapiens (ヒト)
キーワード	NUCLEAR PROTEIN / NUCLEAR RECEPTOR HORMONE RECEPTOR PREGNANE X RECEPTOR