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-Structure paper
Title | Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. |
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Journal, issue, pages | Elife, Vol. 10, Year 2021 |
Publish date | Nov 2, 2020 (structure data deposition date) |
![]() | Chen, X. / Ali, Y.I. / Fisher, C.E. / Arribas-Bosacoma, R. / Rajasekaran, M.B. / Williams, G. / Walker, S. / Booth, J.R. / Hudson, J.J. / Roe, S.M. ...Chen, X. / Ali, Y.I. / Fisher, C.E. / Arribas-Bosacoma, R. / Rajasekaran, M.B. / Williams, G. / Walker, S. / Booth, J.R. / Hudson, J.J. / Roe, S.M. / Pearl, L.H. / Ward, S.E. / Pearl, F.M. / Oliver, A.W. |
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Methods | X-ray diffraction |
Resolution | 1.53 - 2.96 Å |
Structure data | ![]() PDB-7auc: ![]() PDB-7aud: |
Chemicals | ![]() ChemComp-ACT: ![]() ChemComp-EDO: ![]() ChemComp-PG4: ![]() ChemComp-GOL: ![]() ChemComp-ADP: ![]() ChemComp-MG: ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-HOH: ![]() ChemComp-RY8: |
Source |
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![]() | NUCLEAR PROTEIN / Helicase / RecQ / BLM / DNA Repair / Inhibitor / Allosteric |