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-Structure paper
Title | NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir. |
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Journal, issue, pages | Cell Chem Biol, Vol. 28, Page 1693-1702.e6, Year 2021 |
Publish date | Oct 14, 2020 (structure data deposition date) |
![]() | Zhang, S.M. / Rehling, D. / Jemth, A.S. / Throup, A. / Landazuri, N. / Almlof, I. / Gottmann, M. / Valerie, N.C.K. / Borhade, S.R. / Wakchaure, P. ...Zhang, S.M. / Rehling, D. / Jemth, A.S. / Throup, A. / Landazuri, N. / Almlof, I. / Gottmann, M. / Valerie, N.C.K. / Borhade, S.R. / Wakchaure, P. / Page, B.D.G. / Desroses, M. / Homan, E.J. / Scobie, M. / Rudd, S.G. / Berglund, U.W. / Soderberg-Naucler, C. / Stenmark, P. / Helleday, T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.95 - 2.35 Å |
Structure data | ![]() PDB-7aom: ![]() PDB-7aop: |
Chemicals | ![]() ChemComp-RQ2: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-RTW: |
Source |
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![]() | HYDROLASE / NUDIX hydrolase / antiviral / inhibitor |