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-Structure paper
Title | Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein-Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases. |
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Journal, issue, pages | J. Med. Chem., Vol. 65, Page 8828-8842, Year 2022 |
Publish date | Oct 8, 2020 (structure data deposition date) |
![]() | Andrews, M.D. / Dack, K.N. / de Groot, M.J. / Lambert, M. / Sennbro, C.J. / Larsen, M. / Stahlhut, M. |
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Methods | X-ray diffraction |
Resolution | 2.48 - 3.18 Å |
Structure data | ![]() PDB-7ama: ![]() PDB-7amg: |
Chemicals | ![]() ChemComp-RMK: ![]() ChemComp-HOH: ![]() ChemComp-RMQ: |
Source |
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![]() | IMMUNE SYSTEM / interleukin IL-17A inhibitor receptor |