+Search query
-Structure paper
Title | Tenofovir-Amino Acid Conjugates Act as Polymerase Substrates-Implications for Avoiding Cellular Phosphorylation in the Discovery of Nucleotide Analogues. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 64, Page 782-796, Year 2021 |
Publish date | Sep 25, 2020 (structure data deposition date) |
Authors | Gu, W. / Martinez, S. / Nguyen, H. / Xu, H. / Herdewijn, P. / De Jonghe, S. / Das, K. |
External links | J. Med. Chem. / PubMed:33356231 |
Methods | X-ray diffraction |
Resolution | 2.62 - 3.15 Å |
Structure data | PDB-7ahx: PDB-7aid: PDB-7aif: PDB-7aig: PDB-7aii: PDB-7aij: |
Chemicals | ChemComp-MN: ChemComp-REK: ChemComp-HOH: ChemComp-RE5: ChemComp-RFE: |
Source |
|
Keywords | TRANSFERASE / reverse transcriptase RT inhibitor complex tenofovir analog RT-DNA complex / reverse transcriptase / RT inhibitor complex / tenofovir analog / RT-DNA complex |