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TitleSystematic ""foldamerization"" of peptide inhibiting p53-MDM2/X interactions by the incorporation of trans- or cis-2-aminocyclopentanecarboxylic acid residues
Journal, issue, pagesEur. J. Med. Chem., Vol. 208, Page 112814-, Year 2020
Publish dateSep 13, 2020 (structure data deposition date)
AuthorsFortuna, P. / Twarda-Clapa, A. / Skalniak, L. / Ozga, K. / Holak, T.A. / Berlicki, L.
External linksEur. J. Med. Chem. / Search PubMed
MethodsX-ray diffraction
Resolution2.07 Å
Structure data

PDB-7ad0:
X-ray structure of Mdm2 with modified p53 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / p53 / Mdm2 / MdmX / protein-protein interaction / inhibitor / cancer

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